Building a microfluidics platform is no longer the feat it was a decade ago, and both academic and commercial fabrication facilities have emerged to help, says Deplancke. Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. As an independent group leader of the Laboratory of Systems Biology and Genetics (LSBG) at the EPFL, he succeeded in establishing and sustaining an internationally recognized, interdisciplinary research group with expertise in systems genetics, bioinformatics, and regulatory genomics. Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily. K. Hens, J Feuz, A. Isakova, A. Iagovitina, A. Massouras, J. Bryois, P. Callaerts, S.E. You are currently offline. He is a full professor at EPFL (École Polytechnique Fédérale de Lausanne), where he leads the laboratory of systems biology and genetics. [23], In 2017, he was elected to the National Research Council of the Swiss National Science Foundation. EPFL is Europe’s most cosmopolitan technical university with students, professors and staff from over 120 nations. An engineered approach to study gene regulation, and why home is where the heart is. Bart Deplancke Laboratory of Systems Biology and Genetics (LSBG) EPFL-SV-IBI-LBSG. Cell Reports 2019. A. Massouras, K. Hens, C. Gubelmann, C. Chidley, S. Uplekar, F. Decouttere, J. Rougemont, K. Johnsson, S.T. Auf LinkedIn können Sie sich das vollständige Profil ansehen und mehr über die Kontakte von Bart Deplancke und Jobs bei ähnlichen Unternehmen erfahren. Author pages are created from data sourced from our academic publisher partnerships and public sources. Get the most important science stories of the day, free in your inbox. Bart Deplancke (born 21 August 1975) is a Belgian biologist and researcher. +41 21 693 18 21, EPFL SV IBI-SV UPDEPLA SV 3820 (Bâtiment SV) Station 19 CH-1015 Lausanne, +41 21 693 18 21 [1], Deplancke studied biochemical engineering at Ghent University and graduated with a Master of Science in 1998. https://doi.org/10.1038/nmeth.4188, Nature Methods RelSci Relationships are individuals Bart Deplancke likely has professional access to. Cole, B. Deplancke. Deplancke completed his master's degree in bioengineering at Ghent University and did his PhD work in immunobiology at the University of Illinois at Urbana–Champaign. He relaxes with audiobooks, usually nonfiction, from Thomas Piketty's Capital in the Twenty-First Century to Walter Isaacson's biography of Steve Jobs and Bill Bryson's travel stories. His device, approximately the size of a microscope slide, captures TF–DNA complexes in tiny alcoves. Nat Methods 14, 211 (2017). He and Deplancke have stayed in touch since they began meeting at conferences as postdoctoral fellows on different continents and then after they started labs. However, these microarray data fail to reveal the transcription regulatory mechanisms that underlie, Genomic Variation and Its Impact on Gene Expression in Drosophila melanogaster, Understanding the relationship between genetic and phenotypic variation is one of the great outstanding challenges in biology. C. Gubelmann, A. Isakova, S.M. Bart Deplancke Credit: Nele Gheldof The genome is “our unifying subject,” says Bart Deplancke, a biological systems engineer at the École Polytechnique Fédérale de Lausanne (EPFL). Internet Explorer). “Once built, the platform does not require much maintenance, since the micro chips used for experiments are disposable,” he says. [5][6] In 2007, he established his own lab at EPFL, where he was successively promoted to associate professor in 2014, and to full professor in 2020. Bart Deplancke Associate Professor at Ecole Polytechnique Fédérale de Lausanne (EPFL) Lausanne und Umgebung, Schweiz 500+ Kontakte The genome is “our unifying subject,” says Bart Deplancke, a biological systems engineer at the École Polytechnique Fédérale de Lausanne (EPFL). “Home is where my family is,” he says, referring to his wife and two sons. Software to detect positive interactions in 384-well format in yeast one- and two-hybrid screens (Hens et al., Nature Methods, 2011). Local: SV 3823 5 Pennsylvania Plaza 15th Floor École Polytechnique Fédérale de Lausanne, Ghent University. Julie Russeil Lab manager; Post-Docs. A stromal cell population that inhibits adipogenesis in mammalian fat depots. He joined the EPFL faculty in 2007 and has been an associate professor in the lab of systems biology and genetics since 2014. © 2020 Relationship Science LLC. View phone numbers, addresses, public records, background check reports and possible arrest records for Bart Deplancke. Biočanin, Marjan, Johannes Bues, Riccardo Dainese, Esther Amstad, and Bart Deplancke. Lab on a Chip (2019), BRB-seq: ultra-affordable high-throughput transcriptomics enabled by bulk RNA barcoding and sequencing. Then, a computational pipeline his EPFL colleague Philipp Bucher developed helps to find TF motifs, the sites where TFs bind DNA. Genome biology (2020), Systems-Genetics-Based Inference of a Core Regulatory Network Underlying White Fat Browning. sponsored by Bart Deplancke. Vincent Gardeux Senior bioinformatician. He kept his device design simple, avoiding components that might lead to microchannel clogging. In chronic viral infections, CD8⁺ T cells become functionally deficient and display multiple molecular alterations. Suivez-nous sur Twitter. any kind between RelSci and Bart Deplancke. Professeur ordinaire Empower Your Business Applications with Industry-Leading Relationship Data from the RelSci API. Single cell biology Les étudiants sont exposés à des approches expérimentales et analytiques spécifique des études biologiques dans des cellules individuelles, … EPFL > E > E-DOC > EDBB-ENS, vCard Correspondence to Bart Deplancke. volume 14, page211(2017)Cite this article. +41 21 693 18 21 Fax +41 21 693 09 80 bart.deplancke@epfl.ch deplanckelab.epfl.ch In 2002, he obtained a PhD in immunobiology from the University of Illinois at Urbana-Champaign for his studies on intestinal host-microbe interactions and innate immunity. [24], EPFL (École Polytechnique Fédérale de Lausanne), University of Illinois at Urbana-Champaign, American Society for Nutritional Sciences, "Selective growth of mucolytic bacteria including Clostridium perfringens in a neonatal piglet model of total parenteral nutrition", "Microbial modulation of innate defense: goblet cells and the intestinal mucus layer", "A Gateway-Compatible Yeast One-Hybrid System", "A Gene-Centered C. elegans Protein-DNA Interaction Network", "Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network", "ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer", "Integrative Genomics Identifies the Corepressor SMRT as a Gatekeeper of Adipogenesis through the Transcription Factors C/EBPβ and KAISO", "Scientists Might Have Figured out How to Stop People from Getting Fat", "A stromal cell population that inhibits adipogenesis in mammalian fat depots", "Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription", "Population Variation and Genetic Control of Modular Chromatin Architecture in Humans", "The Genetics of Transcription Factor DNA Binding Variation", "Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines", "Mitochondrial haplotypes affect metabolic phenotypes in the Drosophila Genetic Reference Panel", "Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence", "cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel", "Enteric infection induces Lark-mediated intron retention at the 5′ end of Drosophila genes", "SNSF Research Council: six new members elected - SNF", Bart Deplancke's profile on Google Scholar, https://en.wikipedia.org/w/index.php?title=Bart_Deplancke&oldid=983899892, École Polytechnique Fédérale de Lausanne faculty, University of Illinois at Urbana–Champaign alumni, Short description is different from Wikidata, Pages using infobox academic with unknown parameters, Wikipedia articles with ORCID identifiers, Wikipedia articles with WORLDCATID identifiers, Creative Commons Attribution-ShareAlike License, This page was last edited on 16 October 2020, at 22:42. Il a ensuite effectué son doctorat en immunologie intestinale à l’Université de l’Illinois à Urbana-Champaign (Etats-Unis). Whereas unicellular networks have been studied extensively, metazoan. Deplancke is from Belgium; he spent a decade in the United States and has been in Switzerland almost as long. Verified account Protected Tweets @; Suggested users bart deplancke group About SIB. Né à Courtrai (Belgique) en 1975, Bart Deplancke a fait des études de génie biochimique à l’Université de Gand (Belgique). Bart Deplancke is affiliated with “You just take a 'fresh' chip, plug it in and SMiLE.”. It is considered a Public Ivy and is a member of the Association of American Universities. Ideas come to him in hot showers and on long runs through a nearby forest. Harness the power of your relationships with RelSci Pro, the powerful platform for identifying relationship-driven business opportunities and connections that can propel your career forward. The use of any trade name or trademark is for identification and “The more people join the field, the better,” he says. Article  reference purposes only and does not imply any association with the trademark holder. Statut: Personnel, EPFL SV SV-DEC SV-DO [1][9] In particular, Deplancke uses adipogenesis as a model system to better understand the regulatory networks driving cellular differentiation, focusing on the role of transcription factors[10][11] and transcriptional co-regulators. Isakova, A. et al. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. “I love to withdraw in my music studio and tinker away on my piano and computer software to make music,” he says. A relationship does not necessarily indicate a personal connection. Lab on a Chip (2019). Thank you for visiting nature.com. New York, NY 10001. Deplancke's latest project helps to quantitatively probe the binding of transcription factors (TFs) to DNA. In this conversation. Nature Methods Tel. +41 21 693 71 05 Local: SV 3823 TFs act alone and in pairs, and pairing can change the way they bind to DNA. [2][3][4] He then pursued postdoctoral studies in the laboratories of Marc Vidal (Harvard Medical School) and Marian Walhout (University of Massachussetts), where he developed a high-throughput protein-DNA interaction screening approach and worked on elucidating metazoan genetic regulatory networks. Yongguo Li, Petra C.Schwalie, Andrea Bast-Habersbrunner, Sabine Mocek, Julie Russeil, Tobias Fromme, Bart Deplancke, Martin Klingenspor. Bevers, R. P., Litovchenko, M., Kapopoulou, A., Braman, V. S., Robinson, M. R., Auwerx, J. Non-regulatory role of chromatin in the modulation of expression and complex disease causality, Variable Chromatin Modules (VCM) as a causal non-coding variants. These tunes are not intended for wider consumption, but he wonders what it might feel like when people sing or dance to one's own music. Vincent Gardeux, Fabrice David, Bart Deplancke. Bioinformatics, 2017), Gene- or transcript-specific primer design for real-time PCR (Gubelmann et al., Database, 2012), Primer-initiated de novo sequence synthesis for clone identification (cDNA screens), validation, and genomic annotation (indels) (Massouras et al., Nature Methods, 2010), Detection of amplification-biased sites in allele-specific analysis of ChIP-seq data (Waszak et al., Bioinformatics, 2014), "Transcription factor-DNA Interaction Detection in Yeast". Semantic Scholar profile for Bart Deplancke, with 319 highly influential citations and 137 scientific research papers. Analyzing TF binding is hard: there are many heterodimers, TFs often are not well expressed or don't bind in vitro the way they do in vivo. Sehen Sie sich das Profil von Bart Deplancke im größten Business-Netzwerk der Welt an. Aurelia Tacchini Administration assistant; Lab Managers. the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Bart Deplancke graduated as a Biochemical Engineer at Ghent University (Belgium, 1998) after which he pursued doctoral studies in Immunobiology at the University of Illinois (USA). Ethics declarations. Statut: Personnel, EPFL E E-DOC EDBB-ENS In recent years, tetracyclines, such as doxycycline, have become broadly used to control gene expression by virtue of the Tet-on/Tet-off systems. Professeur ordinaire Morphological and molecular characterization of adult midgut compartmentalization in Drosophila. The University of Illinois at Urbana–Champaign is the second oldest public university in the state (after Illinois State University), and is a founding member of the Big Ten Conference.

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